The human body is both complex in its function and fascinating in its capabilities. There are multiple hormones and proteins and many other things that are working together simultaneously to keep the human body working like a well-oiled machine.
Anything that alters or hinders this process will result in the our body responding to the lost function by giving us few signs that will help us recognize where in the body is the problem and how can we fix it.
Hormones controls our body’s day to day functions, such as our sleep, temperature, appetite, growth, weight and many more.
Out of many hormones in our body, today we will focus on Growth Hormone also popularly known to many as human growth hormone (HGH).
What is a Growth Hormone?
Growth
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Due to his tall stature, he faced many complications and died a young man at age 22. His height at the time of death was 8 ft 11 inches. He was also given title as “Giant of Illinois”. His birth place being Illinois, USA.
How do we test for Growth hormone deficiency and excess?
GH Excess
a. A blood test to measure the levels of GH and IGF-1
b. Oral glucose test: during this test the child is asked to consume a drink containing glucose. Blood samples are taken after the drink is consumed. In a normal scenario the GH levels should drop after drinking glucose. But if the GH does not drop and remains the same, its an indication that the body is making too much GH.
c. Imaging
GH Deficiency
In the case of GH deficiency, measurement of GH in the blood is not very helpful for the sake of diagnosis. However the most frequently used test is the Insulin tolerance test (ITT).
The base of this test is that, insulin decreases the blood sugar levels in the body and this acts as a stimulant for the gland to release GH. Samples are collected every 2 hours to see if the GH is increased. In the GH deficiency the GH levels do not rise.
What are some of the treatments used for conditions caused by GH excess or GH
The supply of glucose to the brain and immune system is important as competitors constantly rely on instantaneous decision making to ensure they make effective strategic moves. Glucagon is the hormone which ultimately increases blood glucose concentration by breaking down stored glycogen in muscle and fat cells, increasing the breakdown of fats and increasing liver glucose production. Each of these effects lead to an increased amount of glucose present in the bloodstream, meaning more energy for body cells. When the level of glucose in the bloodstream drops, more glucose is required in order to provide ATP for energy. The secretion of insulin by beta cells is inhibited
Subject X’s reading result was 7.4 mmol/L. The results of a fasting test with respect to glucose levels in the body are: Normal: 3.9 to 5.5 mmol/l (70 to 100 mg/dl). Prediabetes or Impaired Glucose Tolerance: 5.6 to 7.0 mmol/l (101 to 126 mg/dl). Diagnosis of diabetes: more than 7.0 mmol/l (126 mg/dl).
If Eric is growing too quickly due to excess GH and not producing enough testosterone due to low LH and FSH then he would experience low bone mass. Testosterone is also responsible for the hardening of the ends of the bones. When the ends of the bones are not hardening as they should due to rapid growth and low testosterone the result is joint damage. This would explain why Eric’s doctor could not find a cause to his joint damage when they removed 500cc’s
Many patients coming for regular check up are diagnosed as diabetes. The normal random blood sugar is 80 mg to 140 mg. The persistent hyperglycemia leads to many complications in the long run like neuropathy, nephropathy, CAD, foot ulcer and gangrene resulting finally in amputation of the limb. The high blood glucose causes the cell walls to become stiff and rigid, impairing the flow of blood throughout the small vessels located at the surface of the wound. This reduces the blood flow and permeability of red blood cells, which are required for the development of dermal tissue.
Moreover, I held the health education for them and helped them learn to use the blood sugar monitor correctly. I also presented several examples to explain the seriousness of exacerbating diabetes. Patients will have many complications, such as diabetic retinopathy, diabetic cardiomyopathy, diabetic nephropathy and etc. Furthermore, I demonstrated how the blood sugar monitors work face to face. Make them understand that it is very useful and convenient for them to know well their blood sugar level, what is more, to control their health at any
The liver produces hormones and proteins, in addition to cholesterol and affects the way the body grows and heals. It also converts existing amino acids into proteins and creates new amino acids. And it is these proteins that are the building blocks of the hormones,
Reference list Bourne, R. R., G. A. Stevens, R. A. White, J. L. Smith, S. R. Flaxman, H. Price, J. B. Jonas, J. Keeffe, J. Leasher, K. Naidoo, K. Pesudovs, S. Resnikoff, H. R. Taylor & G. Vision Loss Expert (2013) Causes of vision loss worldwide, 1990-2010: a systematic analysis. Lancet Glob Health, 1, e339-49. Emerging Risk Factors, C., N. Sarwar, P. Gao, S. R. Seshasai, R. Gobin, S. Kaptoge, E. Di Angelantonio, E. Ingelsson, D. A. Lawlor, E. Selvin, M. Stampfer, C. D. Stehouwer, S. Lewington, L. Pennells, A. Thompson, N. Sattar, I. R. White, K. K. Ray & J. Danesh (2010) Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies.
Ice Break questions: 1. If you have questions about these kind of subjects, you can talk to a doctor and ask advice to family members. Doctors have studied it and are specialized in it so they can help you a lot with it. Family members are always helpful for advice, because they experienced it in the past. 2.
Type 2 diabetes mellitus is a heterogeneous syndrome characterized by abnormalities in carbohydrate and fat metabolism. Also known as "on-set diabetes" or "non-insulin-dependent diabetes". Factors that set the influence of developmening diabetes are genetic, metabolic, microbiologic and immunologic. Genetic factors include etiology of diabetes because it runs in the families. Metabolic factors involved in the etiology of diabetes are several and complex.
These two hormones help regulate plasma glucose, also referred to as blood glucose, levels. Glucagon increases blood glucose and Insulin decreases blood glucose levels. When blood glucose levels are too low, Glucagon sends a message for the glycogen to be broken down into glucose to be released into the blood.
Every one of us knows that testosterone is the quintessential male hormone. In the physical sense, it is what makes a man a man. The primary male hormone plays a major role in the development of male reproductive issues as well in in the such secondary sexual characteristics as body mass, muscle strength, and body hair. In puberty, it builds our muscles, deepens our voices, grows our beards, and increases the size of our penis and testes. Thank you very much!
The patients who are suffering from diabetes of any age will include as indicator. 2. Doctors- The physicians to follow up with patients through medication, pathology etc. 3.
I want you all to imagine a world with no diseases and maybe even no cancer. Seems pretty impossible right? Well, with gene therapy that could all change. B. Background and Audience Relevance: Gene therapy is essentially using genes as drugs for the treatment of human disease. In the future, this experimental technique may allow doctors to treat a disorder by inserting a gene into a patient’s cells instead of using medicine or surgery.
First, it would be important to know the sensitivity of many people who are at risk to develop this disorder. Second, the specificity of how many people who are being affected by diabetes in order to start the treatment and to prevent more complications. This could be considered as the most difficult level because not everyone will be complied with the screening process. Next, other aspect that can be affected the screening outcomes is the implications of false negative and false positive results which are inevitable given to the people that have been screening. Last, screening is costly effective.
The endocrine system is such an important system to the body because it functions the bodies use of hormones. The body uses many different hormones and the endocrine system regulates these. When the glands of the endocrine system secrete the hormones, the hormones are put into the bloodstream to be sent to the different parts of the body. The glands that comprise the endocrine system are the hypothalamus, the pituitary gland, and the pineal gland which are all located in the brain, the thyroid, parathyroid, and thymus which are located in the throat, the adrenals and pancreas which are located in the body’s midsection, and the ovaries (female) and testes (male) which are located in the pelvic region. The system is so important because it regulates the body’s metabolism, growth and sexual development, digestion, heart rate, and many of the other body functions regulated by hormones.