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Toluene Solubility

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Solubility of the compound was determined in different solvents like hydrochloric acid, sul-furic acid, sodium hydroxide, methanol, ethanol, acetone, ethyl acetate, chloroform, DMSO, glacial acetic acid, n-hexane, cyclohexane, n-octanol, diethyl ether, benzene, toluene and wa-ter, followed by the preparation of saturated solution with those solvents which shows good solubility with the synthesized compound and then plotted a linear calibration curve to de-termine the concentration. The solubility determination was based on the USP Criteria (Low Y and Law SL., 1996; Lalitha Y and Lakshmi PK., 2011).

2.7.3. pH
10 mg of the synthesized compound was weighed accurately and placed into three separate volumetric flasks containing suitable solvents

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